Fatma Deniz SAYINER1
1EskiÅŸehir Osmangazi University Faculty of Health Sciences, TURKEY
Title: Effects of Environmental Conditions on the Birth Process and Some of the Labor Hormones
Biography
Biography: Fatma Deniz SAYINER1
Abstract
The aim of this study was to compare the effect of environmental conditions on the birth hormones and labor process of pregnant rats. A total of 18 pregnant Sprague Dawley rats were divided into control, stress and enriched group. Animals in the stress group were exposed to unexpected variable stress paradigm three times a day during their pregnancy third trimester. Whereas animals raised in enriched environment were raised in larger cages equipped with different toys and shelters. All rats were subjected to open field test for 5 minutes in the last trimester. Blood samples were taken from the tail vein at the beginning of birth, and ten parameters (including Corticotropin-releasing hormone , oxytocin, endorphin, epinephrine, norepinephrine, prolactin, estrogen, progesterone, vasopressin and Brain Derived Neurotrophic Factor) involved in labor were assessed.
Kruskal Wallis and Mann Whitney U tests were used to compare data by using MedCalc Statistical Software program (version 12.7.7). Correlation of two continuous variables that did not display normal distribution was done by Spearman's rho correlation analysis.
Interactions of hormones and environmental conditions were significantly different among the groups. While the hormonal interactions in the control group were similar to the physiological parameters, while in other groups this situation displayed variations. There were significant (p<0.05) differences in the values of Corticotropin Relasing Hormone (CRH) and Vasopressin hormone levels. In the open field test, vertical standing scores of animals displayed differences among control, stress and enriched environment groups (p<0.05).
These results showed that labor environment diversely affects the physiology of birth. Therefore, the birth environment, either at home or at the hospital, needs to be well-organized accordingly. While organizing the environment, it is recommended that all unnecessary materials are removed from the birth scenery and replaced with women-specific materials.